Millipore Corporation has introduced the Viresolve Pro Solution system, a new system for purification of viruses. The technology in the new platform includes a

2016-09-21 · 7 • Rely on LRV data provided by vendors • All filters demonstrate similar clearance of small viruses (18-24 nm) Pre-Filter Viral Filter Vendor Viral Filter Composition MMV LRV PPV LRV 0.1 µm PES (VPF, Shield H beta evaluated) Viresolve® Pro (Vpro) EMD Millipore PES Asymmetric Membrane 5.8 N/A4.8 5.7 0.1 µm PES Planova® 15N Asahi Kasei Bioprocess Regenerated Cellulose Hollow Fiber N/A

Each kit contains 9 Micro devices from one membrane layering combination*, a user guide and certificate of quality. The air vent prevents air locking within the device. * Viresolve Pro devices are Viresolve Pro Modus 1.3 Device; find Millipore-VPMD103NB1 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich. Viresolve® Pro Shield H Kit Small scale devices for process development, optimization and validation studies Membrane based adsorptive prefilters to remove protein aggregates and other fouling species Nine units per kit (one membrane lot) Features of the Viresolve Pro+ Solution virus filter include a proprietary binary gas integrity test to detect the presence of oversized pores or defects which can compromise a filter’s retention capability and cause contamination in the end product. Description Catalogue Number VPMD103NB1 Trade Name Viresolve® Description Viresolve® Pro Modus 1.3 Device Product Information Device Configuration Modus 1.3 Device Connections, Inlet/Outlet Inlet/outlet: 3/4″ sanitary TC fittings Connections, Vent/Drain Integrated […] Viresolve ® Description Viresolve® Pro Magnus 2.1 Device Device Configuration Magnus 2.1 Device Connections, Inlet/Outlet Disposable 1.5" sanitary TC fittings Connections, Vent/Drain Vent: disposable 3/4" sanitary TC fitting for the port Millipore Corporation’s new Viresolve Pro and Pro+ solutions are a major leap forward in virus clearance technology. As biotech manufacturers experience high titers, the evolution of process platforms and increasing focus on cost of goods, the demand for a robust high-capacity unit operation is increasing. The Viresolve Pro device comprises two layers of polyether sulfone (PES) flat-sheet membrane with a 3.1 cm 2 filtration area.

Viresolve pro

This robust filter configuration improves NFP filter capacity significantly reducing your overall virus filtration costs. Rapid, Reliable Composed of a PVDF material, Viresolve NFP membranes possess a unique pore structure with characteristics that enhance filtration efficiency. Viresolve® Pro Shield H removes protein aggregates and impurities that foul virus filters in high pH and high conductivity monoclonal antibody (mAb) feed streams. Combined with Viresolve® Pro Device parvovirus retentive filters, the Viresolve® Pro Shield H significantly increases processing capacity, Viresolve® Pro Shield and Shield H Selection Guide Data Sheet Size based membrane filtration provides critical virus removal assurance in most established and new biopharmaceutical molecule production processes.

Viresolve Pro –Process Disruption Filtration Red virus filtered before pressure release, green after pressure release Diffuse band observed for both colors within depth of filter Green virus seem to penetrate deeper into filter, moving past the red viruses Very different behavior than DV20 Red image Green Image

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2016-09-21

Each Viresolve® Pro Micro 40 Device is packaged in a blister pack and labeled with the device lot and the top layer membrane lot/roll number. Every Viresolve® Pro Micro Device undergoes a Binary Gas Test before product release ensuring optimum quality and performance consistency.

Every Viresolve® Pro Micro Device undergoes a Binary Gas Test before product release ensuring optimum quality and performance consistency.
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As biotech manufacturers experience high titers, the evolution of process platforms and increasing focus on cost of goods, the demand for a robust high-capacity unit operation is increasing. The Viresolve Pro device comprises two layers of polyether sulfone (PES) flat-sheet membrane with a 3.1 cm 2 filtration area.

Combined with Viresolve® Pro Device parvovirus retentive filters, the Viresolve® Pro Shield H significantly increases processing capacity, while preserving high virus Viresolve Pro –Process Disruption Filtration Red virus filtered before pressure release, green after pressure release Diffuse band observed for both colors within depth of filter Green virus seem to penetrate deeper into filter, moving past the red viruses Very different behavior than DV20 Red image Green Image Viresolve Pro Shield H removes protein aggregates and impurities that foul virus filters in high pH and high conductivity monoclonal antibody (mAb) feed streams. Combined with Viresolve Pro Device parvovirus retentive filters, the Viresolve Pro Shield H significantly increases processing capacity, while preserving high virus removal and high flux.
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Viresolve Pro –Process Disruption Filtration Red virus filtered before pressure release, green after pressure release Diffuse band observed for both colors within depth of filter Green virus seem to penetrate deeper into filter, moving past the red viruses Very different behavior than DV20 Red image Green Image

Merck Millipore Viresolve™ Pro Micro Device PD and Validation Kit Viresolve™ Pro Micro Device PD and Validation Kit is suited for performing filter sizing and virus validation studies. Brand: Merck Millipore VPMNVALNB9 Product Code. 15830120 Viresolve® Pro Virus Filtration High mass capacity High flux for faster processing of large batches Disposable flow path with no cleaning validations required Caustic stable Easy and fast setup for minimal labor Easy to integrity test via air-water diffusion testing Viresolve® Pro/Pro+ Magnus Holder Options for using Viresolve® Pro Devices with or without Shield/Shield H prefiltration No product contact eliminates the need for cleaning validations Simple manual hydraulics to clamp units Vertical orientation to minimize footprint and facilitate use (stack, Viresolve® Pro/Pro+ Magnus Holder Options for using Viresolve® Pro Devices with or without Shield/Shield H prefiltration No product contact eliminates the need for cleaning validations Simple manual hydraulics to clamp units Vertical orientation to minimize footprint and facilitate use (stack, The Viresolve Pro Shield and Viresolve® Pro Shield H adsorptively remove impurities and other potential foulants that can plug the Viresolve® Pro Device and lead to decreased capacity. Figure 2 illustrates the optimal performance of the Viresolve® Pro Shield and Shield H, … Every Viresolve® Pro Micro Device undergoes a Binary Gas Test before product release ensuring optimum quality and performance consistency. Viresolve® Pro Devices are built with two membrane layers.

Every Viresolve® Pro Micro Device undergoes a Binary Gas Test before product release ensuring optimum quality and performance consistency. Viresolve® Pro Devices are built with two membrane layers. Each Viresolve® Pro Micro 40 Device is packaged in a blister pack and labeled with the device lot and the top layer membrane lot/roll number.

Refer to the Viresolve Pro Micro Device User Guide for Filtering instructions. Integrity Testing Integrity testing of the Viresolve Pro Micro Shield is not required. 1. Viresolve Pro Modus 1.3 Device; find Millipore-VPMD103NB1 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich. The Viresolve Pro PD kit is ideally suited for performing your evaluation, optimization and scaling studies. Each kit contains 9 Micro devices from one membrane layering combination*, a user guide and certificate of quality. The air vent prevents air locking within the device.

The protein PfRH5 is an essential blood-stage infection facilitator of malarial parasite Viresolve® Pro Virus Filtration High mass capacity High flux for faster processing of large batches Disposable flow path with no cleaning validations required Caustic stable Easy and fast setup for minimal labor Easy to integrity test via air-water diffusion testing Viresolve® Pro/Pro+ Magnus Holder Options for using Viresolve® Pro Devices with or without Shield/Shield H prefiltration No product contact eliminates the need for cleaning validations Simple manual hydraulics to clamp units Vertical orientation to minimize footprint and facilitate use (stack, The Viresolve Pro Shield and Viresolve® Pro Shield H adsorptively remove impurities and other potential foulants that can plug the Viresolve® Pro Device and lead to decreased capacity.